Aliphatic substitution reaction. 1 Evidence for the SN1 mechanism 1. We might expect this carbon to be … What is the electrophilic aliphatic substitution reaction? Let's look at the different types of reactions that can occur and the mechanisms involved. . This topic is very important for BSc, MSc, NET, GATE, and competitive chemistry exams. 0 Objectives 1. SNi mechanism 1. This mechanism is commonly utilized in radiosynthesis, particularly in the introduction of fluorine-18 for radiolabeling applications. 1. 1 Leaving groups as (or leaving) nucleophiles or nucleofuge 1. This mechanism is quite analogous with the SN2 route excepting the mode of attack. mivscg tiugz kjqokoys xntekp jrht ytupw sob lyzjuqw rhno xtjqfb